Transglutaminase 7 Antikörper

Produktnummer ABIN1077363

Dieses Anti-Transglutaminase 7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Transglutaminase 7 in WB, ELISA, IF und ICC. Geeignet für Human und Maus.

Kurzübersicht für Transglutaminase 7 Antikörper (ABIN1077363)

Target: Transglutaminase 7 (TGM7)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Transglutaminase 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-Transglutaminase 7 Antikörper

Spezifität: TGM7 antibody is predicted to not cross-react with other TGase protein family members. At least two isoforms of TGM7 are known to exist, this antibody will recognize both isoforms.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: TGM7 antibody was raised against a AA 13 synthetic peptide near the center of human TGM7.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TGM7 antibody can be used for detection of TGM7 by Western blot at 1 μg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μg/mL. For immunofluorescence start at 10 μg/mL. Optimal dilutions for each application to be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: TGM7 antibody can be stored at 4° C for three months and -20° C, stable for up to one year.

Details zu Transglutaminase 7

Target: Transglutaminase 7 (TGM7)

Andere Bezeichnung: TGM7

Hintergrund: Synonyms:
Transglutaminase 7, protein-glutamine gamma-glutamyltransferase 7, TGase-7, TGase Z, TGMZ

Transglutaminases (TGM) are a family of structurally and functionally related Ca2+-dependent enzymes (TGases) that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks. TGases influence numerous biological processes, including blood coagulation, cell differentiation, fertilization and apoptosis. TGM7 belongs to the transglutaminase superfamily and is also thought to catalyze the cross-linking of proteins, often resulting in stabilization of protein assemblies. Little is known of the role of TGM7, but defects in the highly related protein TGM5 are associated with acral peeling skin syndrome.

Gen-ID: 116179